研究成果

2024年

Haitao Dou; Zixin Luo; Haodun Wang; Qicheng Duan; Zhuangzhuang Jiang; Huachao Chen; Ninghua Tan. Tumor microenvironment-responsive intelligent nanoplatform with oxygen self-supply for synergistic chemotherapy/photodynamic therapy/photothermal therapy against hypoxic tumors. Chemical Engineering Journal. 10.1016/j.cej.2024.150523

2023年

Ling-Yun Chen, Bei Lu, Diego F. Morales-Briones, Michael L. Moody, Fan Liu, Guang-Wan Hu, Chien-Hsun Huang, Jin-Ming Chen, Qing-Feng Wang, Phylogenomic Analyses of Alismatales Shed Light into Adaptations to Aquatic EnvironmentsMolecular Biology and Evolution, https://doi.org/10.1093/molbev/msac079

2022年

Li Feng#, Xin-JiaWang#, Ling Li, An-Xin Zhang, Ran-Ran Shang, Ning-Hua Tan* and Zhe Wang* . Identification of meroterpenoids from Bipolaris victoriae S27 and their potential activity against tumor metastasis and inhibition of the NF-κB signaling pathway. Phytochemistry 2022; 200:113180. https://doi.org/10.1016/j.phytochem.2022.113180

2021年及以前

1.Grace G. L. Yue, Jun-Ting Fan, Julia K. M. Lee, Bin Kuang, Guang-Zhi Zeng, Tina W. F. Ho, Kwok-Pui Fung, Ping-Chung Leung, Ning-Hua Tan*, Clara B. S. Lau*. Cyclopeptide RA-V inhibits angiogenesis by downregulating extracellular signal-regulated kinase 1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells. British Journal of Pharmacology, 2011, in press
2.Yishan Chen, Xulin Pan, He Yan, Ninghua Tan*. Multiple hydrogen-bonding interactions between macrocyclic triurea and F-, Cl-, Br-, I- and NO3-: A theoretical investigation. Physical Chemistry Chemical Physics, 2011, 13, 7384-7395
3. Jun-Ting Fan, Jia Su, Yan-Min Peng, Yan Li, Jia Li, Yu-Bo Zhou, Guang-Zhi Zeng, He Yan, Ning-Hua Tan*. Rubiyunnanins C-H, cytotoxic cyclic hexapeptides from Rubia yunnanensis inhibiting nitric oxide production and NF-kB activation. Bioorganic & Medicinal Chemistry, 2010, 18: 8226-8234
4. Jun-Ting Fan, Yi-Shan Chen, Wen-Yan Xu, Liangcheng Du, Guang-Zhi Zeng, Yu-Mei Zhang, Jia Su, Yan Li, Ning-Hua Tan*. Rubiyunnanin A and B, two novel cyclic hexapeptides from Rubia yunnanensis. Tetrahedron Letters, 2010, 51(52): 6810-6813
5. Jun Tang, Conan K. Wang, Xulin Pan, He Yan, Guangzhi Zeng, Wenyan Xu, Wenjun He, Norelle L. Daly, David J. Craik, Ninghua Tan*. Isolation and characterization of cytotoxic cyclotides from Viola tricolor. Peptides, 2010, 31: 1434-1440
6. Jun Tang, Conan K. Wang, Xulin Pan, He Yan, Guangzhi Zeng, Wenyan Xu, Wenjun He, Norelle L. Daly, David J. Craik*, Ninghua Tan*. Isolation and characterization of bioactive cyclotides from Viola labridorica. Helvetica Chimica Acta, 2010, 93(11): 2287-2295
7. He Yan, Xulin Pan, Ninghua Tan*, Junting Fan, Guangzhi Zeng, Hongjin Han. 2D- and 3D-QSAR studies on 54 anti-tumor Rubiaceae-type cyclopeptides. European Journal of Medicinal Chemistry, 2009, 44: 3425-3432 8. Wang, C. K., Hu, S. H., Martin, J. L., Sjogren, T., Hajdu, J., Bohlin, L., Claeson, P., Goransson, U., Rosengren, K. J., Tang, J., Tan, N. H., Craik, D. J. Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold. Journal of Biological Chemistry, 2009, 284(16): 10672-10683
9. Jiang Xiong, Ning-Hua Tan*, Chang-Jiu Ji, Yang Lu, Ning-Bo Gong. Vilmoraconitine A, a novel skeleton C19-diterpenoid alkaloid from Aconitum vilmorinianum. Tetrahedron Letters, 2008, 49: 4851-4853
10. Xu WenYan, Tang Jun, Ji ChangJiu, He WenJun, Tan NingHua*. Application of a TLC chemical method to detection of cyclotides in plants. Chinese Science Bulletin, 2008, 53(11): 1671-1674
11. Yu-Mei Zhang, Ning-Hua Tan*, Yang Lu, Ying Chang, Rui-Rui Jia. Chamobtusin A, a novel skeleton diterpenoid alkaloid from Chamaecyparis obtusa cv. tetragon. Organic Letters, 2007, 9(22): 4579-4581
12. Ning-Hua Tan*, Jun Zhou. Plant cyclopeptides. Chemical Reviews, 2006, 106(3): 840-895
13. Yu-Mei Zhang, Ning-Hua Tan*, Min He, Yang Lu, Su-Qin Shang, Qi-Tai Zheng. Sequosempervirin A, a novel spirocyclic compound from Sequoia sempervirens. Tetrahedron Letters, 2004, 45: 4319-4321
14. Zhou Jun and Tan Ninghua. Application of a new TLC chemical method for detection of cyclopeptides in plants. Chinese Science Bulletin, 2000, 45(20): 1825-1831
15. Ninghua Tan*, Jun Zhou, Shouxun Zhao. Advances in structural elucidation of glucuronide oleanane-type triterpene carboxylic acid 3,28-O-bisdesmosides (1962-1997). Phytochemistry, 1999, 52: 153-192
16. 谭宁华,赵守训,周俊,陈昌祥。九子参苷A的结构。化学学报,1995,53: 1024-1033
17. Tan Ning-hua, Zhou Jun, Chen Chang-xiang, Zhao Shou-xun. Cyclopeptides from the roots of Pseudostellaria heterohylla. Phytochemistry, 1993, 32(5): 1327-1330